Detalhe da pesquisa
1.
Neutrophils and emergency granulopoiesis drive immune suppression and an extreme response endotype during sepsis.
Nat Immunol
; 24(5): 767-779, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37095375
2.
An atlas of genetic scores to predict multi-omic traits.
Nature
; 616(7955): 123-131, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36991119
3.
A Transcriptomic Approach to Understand Patient Susceptibility to Pneumonia After Abdominal Surgery.
Ann Surg
; 279(3): 510-520, 2024 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37497667
4.
Patient stratification using plasma cytokines and their regulators in sepsis: relationship to outcomes, treatment effect and leucocyte transcriptomic subphenotypes.
Thorax
; 2024 Mar 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-38471792
5.
IMPACT: Genomic Annotation of Cell-State-Specific Regulatory Elements Inferred from the Epigenome of Bound Transcription Factors.
Am J Hum Genet
; 104(5): 879-895, 2019 05 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31006511
6.
Blood leukocyte transcriptomes in Gram-positive and Gram-negative community-acquired pneumonia.
Eur Respir J
; 59(3)2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34446464
7.
Shared and Distinct Aspects of the Sepsis Transcriptomic Response to Fecal Peritonitis and Pneumonia.
Am J Respir Crit Care Med
; 196(3): 328-339, 2017 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28036233
8.
Application of whole genome and RNA sequencing to investigate the genomic landscape of common variable immunodeficiency disorders.
Clin Immunol
; 160(2): 301-14, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26122175
9.
A common haplotype of the TNF receptor 2 gene modulates endotoxin tolerance.
J Immunol
; 186(5): 3058-65, 2011 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21282507
10.
Inducible apelin receptor knockdown reduces differentiation efficiency and contractility of hESC-derived cardiomyocytes.
Cardiovasc Res
; 119(2): 587-598, 2023 03 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-36239923
11.
BurkHostGEN: a study protocol for evaluating variations in the Burkholderia pseudomallei and host genomes associated with melioidosis infection.
Wellcome Open Res
; 8: 347, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37928212
12.
Mechanistic study of the effect of Endothelin SNPs in microvascular angina - Protocol of the PRIZE Endothelin Sub-Study.
Int J Cardiol Heart Vasc
; 39: 100980, 2022 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-35242999
13.
Genetically personalised organ-specific metabolic models in health and disease.
Nat Commun
; 13(1): 7356, 2022 11 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-36446790
14.
Transcriptional reprogramming from innate immune functions to a pro-thrombotic signature by monocytes in COVID-19.
Nat Commun
; 13(1): 7947, 2022 12 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-36572683
15.
An immune dysfunction score for stratification of patients with acute infection based on whole-blood gene expression.
Sci Transl Med
; 14(669): eabq4433, 2022 11 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36322631
16.
Interactions Between Genome-Wide Genetic Factors and Smoking Influencing Risk of Systemic Lupus Erythematosus.
Arthritis Rheumatol
; 72(11): 1863-1871, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32969204
17.
Epstein-Barr virus reactivation in sepsis due to community-acquired pneumonia is associated with increased morbidity and an immunosuppressed host transcriptomic endotype.
Sci Rep
; 10(1): 9838, 2020 06 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-32555213
18.
Discovering in vivo cytokine-eQTL interactions from a lupus clinical trial.
Genome Biol
; 19(1): 168, 2018 10 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-30340504
19.
A community approach to mortality prediction in sepsis via gene expression analysis.
Nat Commun
; 9(1): 694, 2018 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29449546
20.
Classification of patients with sepsis according to blood genomic endotype: a prospective cohort study.
Lancet Respir Med
; 5(10): 816-826, 2017 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-28864056